About Enhancer
| Enhancer ID: | E_01_086 | |
| Enhancer symbol: | UBE2C Enhancer | |
| Species: | Human | |
| Position : | chr20:44441255-44444472   |
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| Biosample name: | LNCaP,PC-3 | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer | |
| Disease: | Prostate Cancer | |
| DO: | DOID:10283 | |
| Mesh: | D011471 | |
| Distance from TSS: | <2KB | |
| Pubmed ID: | 21556051 |
| Enhancer experiment: | RT-PCR,Luciferase Reporter Assay,ChIP,3C | |
| Enhancer experiment description: | we performed quantitative 3C assays for the UBE2C locus in LNCaP and PC-3 cells, in order to identify potential PC-3-specific UBE2C enhancers. |
About Target gene
| Target gene : | UBE2C(UBCH10,dJ447F3.2) | |
| Strong evidence: | 3C | |
| Less strong evidence: | RT-PCR,Western blot | |
| Target gene experiment description: | 3C assays were performed at the UBE2C locus to measure crosslinking frequencies between PC-3-specific UBE2C enhancers and the UBE2C promoter |
About TF
| TF name : | FOXA1(HNF3A,TCF3A)GATA2(DCML,IMD21,MONOMAC,NFE1B)POU2F1(OCT1,OTF1,oct-1B)ETS1(ETS-1,EWSR2,c-ets-1,p54) | |
| TF experiment: | ChIP | |
| TF experiment description: | To examine whether these transcription factors were differentially recruited to E1,E2 and E3 on chromatin, chromatin immunoprecipitation (ChIP) assays were performed using specific antibodies against FoxA1, GATA2, Oct1 and ETS1 in LNCaP and PC-3 cells treated with or without DHT. |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
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About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
