About Enhancer

Enhancer ID: E_01_075
Enhancer symbol: --
Species: Human
Position : chr20:8718344-8719933
Biosample name: SK-N-MC
Experiment class : Low throughput
Enhancer type: Enhancer
Disease: Insomnia
DO: --
Mesh: D007319
Distance from TSS: >2KB
Pubmed ID:  21494683
Enhancer experiment: ChIP,PCR
Enhancer experiment description: To investigate histone modification and transcription factor binding, we performed chromatin immunoprecipitation (ChIP) assays using a ChIP assay kit (Millipore, Billerica, MA, USA) according to the manufacturer's protocol.

About Target gene

Target gene : PLCB1(EIEE12,PI-PLC,PLC-154,PLC-I,PLC-beta-1,PLC154A,PLCB1B,)
Strong evidence: --
Less strong evidence: ChIP-seq
Target gene experiment description: The ROR1 SNPs flanked a strong peak of H3K4me1 (Figure 4A) and the PLCB1 SNPs resided near an H3K4me1 peak and two CTCF binding sites (Figure 5A). H3K4me1, often with H3K27ac, is a chromatin marker for enhancers [29]. CTCF is an insulator-binding elementcan interfere with nearby enhancers.

About TF

TF name : PAX6(AN,AN1,AN2,ASGD5,D11S812E,FVH1,MGDA,WAGR)
TF experiment: ChIP,PCR
TF experiment description: Cross ChIP PCR between PAX6 and CTCF. PAX6 ChIP DNA was detected in the two CTCF sites, and CTCF ChIP DNA was detected in the PAX6 site.

About Function

Enhancer function : --
Enhancer function experiment: --
Enhancer function
experiment description:
--

About SNP

SNP ID: --
SNP position: --
SNP experiment: --

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs