Enhancer ID: | E_01_075 | |
Enhancer symbol: | -- | |
Species: | Human | |
Position : | chr20:8718344-8719933 |
|
Biosample name: | SK-N-MC | |
Experiment class : | Low throughput |
Enhancer type: | Enhancer | |
Disease: | Insomnia | |
DO: | -- | |
Mesh: | D007319 | |
Distance from TSS: | >2KB | |
Pubmed ID: | 21494683 |
Enhancer experiment: | ChIP,PCR | |
Enhancer experiment description: | To investigate histone modification and transcription factor binding, we performed chromatin immunoprecipitation (ChIP) assays using a ChIP assay kit (Millipore, Billerica, MA, USA) according to the manufacturer's protocol. |
Target gene : | PLCB1(EIEE12,PI-PLC,PLC-154,PLC-I,PLC-beta-1,PLC154A,PLCB1B,) | |
Strong evidence: | -- | |
Less strong evidence: | ChIP-seq | |
Target gene experiment description: | The ROR1 SNPs flanked a strong peak of H3K4me1 (Figure 4A) and the PLCB1 SNPs resided near an H3K4me1 peak and two CTCF binding sites (Figure 5A). H3K4me1, often with H3K27ac, is a chromatin marker for enhancers [29]. CTCF is an insulator-binding elementcan interfere with nearby enhancers. |
TF name : | PAX6(AN,AN1,AN2,ASGD5,D11S812E,FVH1,MGDA,WAGR) | |
TF experiment: | ChIP,PCR | |
TF experiment description: | Cross ChIP PCR between PAX6 and CTCF. PAX6 ChIP DNA was detected in the two CTCF sites, and CTCF ChIP DNA was detected in the PAX6 site. |
Enhancer function : | -- |
Enhancer function experiment: | -- |
Enhancer function experiment description: |
-- |
SNP ID: | -- | |
SNP position: | -- |
SNP experiment: | -- |
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