Enhancer ID: | E_01_066 | |
Enhancer symbol: | -- | |
Species: | Human | |
Position : | chr1:204123719-204123725 |
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Biosample name: | Calu-6 | |
Experiment class : | Low throughput |
Enhancer type: | Enhancer | |
Disease: | -- | |
DO: | -- | |
Mesh: | -- | |
Distance from TSS: | <2KB | |
Pubmed ID: | 21424707 |
Enhancer experiment: | Luciferase Reporter Assay,PCR | |
Enhancer experiment description: | To test the functional relevance of enhCRE, we fused it to RENMin (construct enhCRE--RENMin). Both cAMP agonists increased the transcriptional activity of enhCRE--RENMin.construct enhCRE--RENMin contains human renin enhancer CRE (enhCRE) fused to RENMin. RLA, relative luciferase activity |
Target gene : | REN(HNFJ2) | |
Strong evidence: | -- | |
Less strong evidence: | Luciferase Reporter Assay | |
Target gene experiment description: | To test the functional relevance of enhCRE, we fused it to RENMin (construct enhCRE--RENMin). Both cAMP agonists increased the transcriptional activity of enhCRE--RENMin.construct enhCRE--RENMin contains human renin enhancer CRE (enhCRE) fused to RENMin. RLA, relative luciferase activity |
TF name : | CAMP(CAP-18,CAP18,CRAMP,FALL-39,FALL39,HSD26,LL37) | |
TF experiment: | Luciferase Reporter Assay,ChIP,qRT-PCR | |
TF experiment description: | Construct RENMin represents the minimal human renin promoter (-199 to +23) which contains the cAMP target sequence CNRE at ?135 to ?107. The PPARγ agonist rosiglitazone (Rosi, 500 nM for 20 h) was applied as positive control;RLA, relative luciferase activity. |
Enhancer function : | -- |
Enhancer function experiment: | -- |
Enhancer function experiment description: |
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SNP ID: | -- | |
SNP position: | -- |
SNP experiment: | -- |
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