About Enhancer

Enhancer ID: E_01_066
Enhancer symbol: --
Species: Human
Position : chr1:204123719-204123725
Biosample name: Calu-6
Experiment class : Low throughput
Enhancer type: Enhancer
Disease: --
DO: --
Mesh: --
Distance from TSS: <2KB
Pubmed ID:  21424707
Enhancer experiment: Luciferase Reporter Assay,PCR
Enhancer experiment description: To test the functional relevance of enhCRE, we fused it to RENMin (construct enhCRE--RENMin). Both cAMP agonists increased the transcriptional activity of enhCRE--RENMin.construct enhCRE--RENMin contains human renin enhancer CRE (enhCRE) fused to RENMin. RLA, relative luciferase activity

About Target gene

Target gene : REN(HNFJ2)
Strong evidence: --
Less strong evidence: Luciferase Reporter Assay
Target gene experiment description: To test the functional relevance of enhCRE, we fused it to RENMin (construct enhCRE--RENMin). Both cAMP agonists increased the transcriptional activity of enhCRE--RENMin.construct enhCRE--RENMin contains human renin enhancer CRE (enhCRE) fused to RENMin. RLA, relative luciferase activity

About TF

TF name : CAMP(CAP-18,CAP18,CRAMP,FALL-39,FALL39,HSD26,LL37)
TF experiment: Luciferase Reporter Assay,ChIP,qRT-PCR
TF experiment description: Construct RENMin represents the minimal human renin promoter (-199 to +23) which contains the cAMP target sequence CNRE at ?135 to ?107. The PPARγ agonist rosiglitazone (Rosi, 500 nM for 20 h) was applied as positive control;RLA, relative luciferase activity.

About Function

Enhancer function : --
Enhancer function experiment: --
Enhancer function
experiment description:
--

About SNP

SNP ID: --
SNP position: --
SNP experiment: --

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs