About Enhancer

Enhancer ID: E_01_016
Enhancer symbol: --
Species: Human
Position : chr13:27523026-27544353
Biosample name: Colon Crypt Cell
Experiment class : Low+High throughput
Enhancer type: Super-Enhancer
Disease: Colorectal Carcinoma
DO: DOID:0080199
Mesh: D015179
Distance from TSS: >2KB
Pubmed ID:  26656844
Enhancer experiment: ChIP-seq,Luciferase Reporter Assay,3C-qPCR,CRISPR/Cas9,siRNA
Enhancer experiment description: Additional focal amplification peaks on chromosome 13q in colorectal carcinoma (CRC) (~21 kb, chr. 13: 27,523,026–27,544,353) and chromosome 20q in liver hepatocellular carcinoma (~22 kb,chr. 20: 48,997,377–49,019,434) were identified. ChIP-seq profiling of H3K27ac in colon crypt cells31 and in the hepatocellular carcinoma cell line HepG2 (ref. 20) demonstrated that these amplicons contain super-enhancers.

About Target gene

Target gene : USP12(UBH1L1)
Strong evidence: --
Less strong evidence: ChIP-seq
Target gene experiment description: Right, log2-transformed expression level (RPKM) of USP12 in CRC tumors with focal amplification of USP12-CCSE (USP12 colorectal carcinoma super-enhancer) alone (n = 6) and tumors without the amplification (n = 127). (Fig. 1d)

About TF

TF name : --
TF experiment: --
TF experiment description: --

About Function

Enhancer function : --
Enhancer function experiment: --
Enhancer function
experiment description:
--

About SNP

SNP ID: --
SNP position: --
SNP experiment: --

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs