About Enhancer
| Enhancer ID: | E_01_013 | |
| Enhancer symbol: | -- | |
| Species: | Human | |
| Position : | chr13:73880690-73990596   |
|
| Biosample name: | BICR-31 | |
| Experiment class : | Low+High throughput |
| Enhancer type: | Super-Enhancer | |
| Disease: | Esophageal Carcinoma | |
| DO: | DOID:1107 | |
| Mesh: | -- | |
| Distance from TSS: | >2KB | |
| Pubmed ID: | 26656844 |
| Enhancer experiment: | ChIP-seq,Luciferase Reporter Assay,3C-qPCR,CRISPR/Cas9,siRNA | |
| Enhancer experiment description: | The focal amplification on chr13q identified in head and neck squamous cell carcinoma (HNSC) (~110 kb, chr13:73880690-73990596) and esophageal carcinoma (ESCA) (~162 kb, chr13:73880413-74042621) |
About Target gene
| Target gene : | KLF5(BTEB2,CKLF,IKLF) | |
| Strong evidence: | -- | |
| Less strong evidence: | ChIP-seq | |
| Target gene experiment description: | The expression of KLF5, but not KLF12, is significantly higher in HNSC tumors with KLF5-HNSE amplification, suggesting that KLF5 is the target gene. |
About TF
| TF name : | -- | |
| TF experiment: | -- | |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
