Subtype diagnostic model

Esophageal cancer (EC) has two proteomic subtypes S1 and S2, of which S2 is a more malignant phenotype with poorer survival outcome. The proteomic subtype of patients with EC can be accurately predicted by a SVM model with a signature composed of ELOA and SCAF4.

There are two ways to predict the subtype of a EC patient, depending on how the protein expression levels of ELOA and SCAF4 are measured.

  • i) If the protein expression levels of ELOA and SCAF4 are H-scores measured by immunohistochemistry (IHC), please select "Input IHC scores" for prediction.
  • ii) If the protein expression levels of ELOA and SCAF4 are protein expression ratios measured by mass spectrometry-based TMT experiments, please select “Input TMT expression ratios” for prediction.