Pathway name:

BMP Signalling Pathway

Aging Type:

Prevent

Aging characteristic:

cellular senescence

Category:

pathway

Phenotype:

Aging

Experimental category:

L

Tissue type:

--

Cell name:

HiPSC,HDF

PMID:

27794120

Experiment:

BrdU assay//SA-β-gal activity assay

Description:

Activating the BMP-SMAD-ID signaling axis increases the cell proliferation rate and decreases cell senescence during iPSC generation.

Pathway Network

Pathway name	Pathway source	Gene number	Edge number	Geneset
BMP Signalling Pathway	humancyc	5	7	ACVR2A;BMP2;BMPR1B;SMAD4;ZFYVE16