External factors
| Category: |
Chemical compounds |
| Experiment: |
SA-β-gal activity assay |
| Description: |
Assay for the senescence marker, SA-β-gal, showed the presence of blue labels for SA-β-gal in the cytoplasm of UA-treated cells. Such staining was not detected in cells treated without UA in the controls. The percentage of SA-β-gal positive cells were 5.27 ± 0.97% in cells treated with 50 μM UA, 17.22 ± 2.67% in 100 μM group, and 23.04 ± 7.42% in 200 μM group, showing a dose dependent increase in senescent cells after UA treatment. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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