External factors
| Experimental category: |
HL |
| Description: |
We found that UVB exposure increased the levels of γH2AX, p16INK4A, and cleaved caspase-3 in the epidermis of wild-type mice, indicating increased senescence and apoptosis. Furthermore,the induction of γH2AX, p16INK4A, and cleaved caspase-3 levels was attenuated in TRPC7+/? and TRPC7?/? mice. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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