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Aging Overview

External factors

External factors: Hypoxia
Aging type: Prevent
Aging characteristic:
Category: Other
Phenotype: Mitochondrial Dysfunction
Experimental category: HL
Tissue type: Heart left ventricle
Cell name: Human Cardiac Progenitor Cell
PMID: 30629785
Experiment: SA-β-gal activity assay
Description: Senescence-associated β-Gal positivity was used as a marker of cellular senescence. hCPC-1% exhibited ~70% fewer SA-β-Gal+ cells than hCPC-21%, suggesting hypoxia delays hCPC senescence and supports self-renewal.



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Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.




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