External factors
| External factors: |
Serum starvation |
| Experiment: |
SA-β-gal activity assay//Western blot |
| Description: |
Alternatively, CDKN2A (cyclin dependent kinase inhibitor 2A), another cell-cycle arrest protein, and a reliable cell senescence marker [25 28] was stably induced in serum-starved fibroblasts. SA-GLB1/β-gal activity, another cell senescence marker [29] was also induced in fibroblasts serum-starved for 7 d. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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