External factors
| External factors: |
Irradiation |
| Experiment: |
SA-β-gal activity assay//Western blot |
| Description: |
For cellular senescence analysis, an SA-βGal assay in NSCLC cells was performed 3 days after irradiation. SA-βGal–positive cells increased significantly in carbon-irradiated A549 cells and in H1299 cells treated with NU7441 and carbon irradiation.p21 expression in A549 cells was consistent with the result of the SA-βGal assay; in contrast, no activation was observed in H1299 cells. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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