External factors
| External factors: |
Ionizing radiation |
| Experiment: |
SA-β-gal activity assay//BrdU assay//Immunostaining |
| Description: |
This abolished cell growth and labelling indices for BrdU, Ki67 and caused expression of senescence-associated β-galactosidase (Sen-β-Gal) to an extent equal to the deep replicative senescence seen when cells had reached their normal proliferative limit. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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