External factors
| External factors: |
Ionizing radiation |
| Experimental category: |
HL |
| Experiment: |
SA-β-gal activity assay//Western blot |
| Description: |
IR-exposed MCF7 cells exhibited specific characteristics of cellular senescence, such as enlarged, flattened morphological changes and positive senescence-associated β-galactosidase staining. These cells also showed pRb hypophosphorylation, p53 accumulation and p21 induction in western blot analyses. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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