External factors
| Category: |
Chemical compounds |
| Phenotype: |
Age-related cataract |
| Experiment: |
SA-β-gal activity assay//Cell morphological analysis |
| Description: |
Morphological changes in SAR01/04 cells began to appear 3 days after exposure to 50 μM H2O2. Two weeks later, the morphology of the treated cells resembled that of senescent cell: with gross enlargement, flattening, and the accumulation of granular cytoplasmic inclusions .In SRA01/04 cells exposed to 50 μM H2O2 for 2 weeks, the proportion of SA-β-gal staining cells was 90.3%±6.2%, but in normal SRA01/04 cells, the SA-β-gal staining was absent . |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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