External factors
| Category: |
Chemical compounds |
| Phenotype: |
Hepatocellular carcinoma |
| Cell name: |
SMMC-7721,HepG2 |
| Experiment: |
SA-β-gal activity assay |
| Description: |
The cell senescence induced by LPD in SMMC-7721 and HepG2 cells.In HepG2 cells with wild-type p53 which is essential for inducing senescence,increased SA-β-gal staining relative to NC-LPD was observed after treatment with RRM2-LPD. More SA-β-gal-positive cells were observed in the ADR-NC-LPD treated group, whereas the ADRRRM2-LPD treated group possessed the most SA-β-gal-positive cells. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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