External factors
| Category: |
Chemical compounds |
| Phenotype: |
Osteoarthritis |
| Cell name: |
Primary mice Chondrocyte,Primary human Chondrocyte |
| Experiment: |
SA-β-gal activity assay//Western blot |
| Description: |
The TBHP-treated chondrocytes exerted higher SA-β-gal activity and p16INK4a protein level relative to the control group, whereas TFEB overexpression significantly prevents this increment. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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