External factors
| External factors: |
3-methyladenine |
| Category: |
Chemical compounds |
| Experiment: |
SA-β-gal activity assay//Annexin V binding assay |
| Description: |
When HUVECs were exposed to NC, tamoxifen-induced cell senescence increased about fourfold, whereas 3-MA affected senescence only marginally. In contrast, exposure of HUVECs to GC alone resulted in a greater than fivefold increase in the proportion of senescent cells, and the presence of 3-MA led to a significant attenuation of development of premature senescence. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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