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Aging Overview

External factors

External factors: Adriamycin
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: HT-1080
PMID: 16204065
Experiment: SA-β-gal activity assay//Flow cytometry
Description: About 50% of the attached cells became senescent after 3 days of Adriamycin treatment. cells were arrested with hydroxyurea, released, and further treated with 30 nmol/L Adriamycin for 5 to 25 hours. Whereas control cells remained growth arrested, 15% of Src-expressing cells had already progressed into mitosis by 10 hours.



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Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.




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