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Aging Overview

External factors

External factors: Bleomycin
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Idiopathic pulmonary fibrosis
Experimental category: L
Tissue type: Lung
Cell name: Fibroblast
PMID: 27979858
Experiment: Western blot//qRT-PCR
Description: In ex vivo experiments, we found that lung epithelial cells of bleomycin-treated WT aged mice demonstrated increased senescent phenotype, as evidenced by greater expression of p21 and PAI-1 in these cells.



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Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.




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