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Aging Overview

External factors

External factors: Chloramphenicol
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: H1299
PMID: 15905168
Experiment: SA-β-gal activity assay//Cell morphological analysis
Description: The photographic images show morphological changes in chloramphenicol-treated H1299 cells. Both cells show blue-violet X-gal crystal accumulation in senescence-associated β-galactosidase staining, suggesting that chloramphenicol-associated mitochondrial stress might trigger senescence biogenesis.The morphology of these chloramphenicol-treated cells was changed to the more flattened, enlarged, and irregular shape characteristic of cell senescence.



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Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.




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