External factors
| External factors: |
Disorazole C1 |
| Category: |
Chemical compounds |
| Experimental category: |
HL |
| Cell name: |
HCT116,H1299,UPCI:SCC103 |
| Experiment: |
SA-β-gal activity assay |
| Description: |
Disorazole C1 treatment resulted in positive β-galactosidase staining even at concentrations below the growth IC50 (1 nM). The percentage of β-galactosidase-positive cells with disorazole C1 treatment was comparable with that seen with doxorubicin. Disorazole C1 also produced positive β-galactosidase human colon cancer (HCT116), lung cancer (H1299), and oral squamous carcinoma (UPCI:SCC103) cells. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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