External factors
| External factors: |
Vemurafenib |
| Category: |
Chemical compounds |
| Cell name: |
M14,Malme 3M,SK-MEL-28,UACC-62 |
| Experiment: |
SA-β-gal activity assay//Flow cytometry//Cell morphological analysis |
| Description: |
In M14 and Malme 3M cells, an increased proportion of the surviving cells was found in G0/G1 after 7 days of Vemurafenib treatment.All cells displaying an enlarged phenotype showed increased senescence-associated β-galactosidase (SA-β-Gal) activity, supporting the notion that Vemurafenibcan induce senescence features in BRAF-dependent melanoma cell lines. |
Warning: Undefined variable $target_genes in
/data/html/Aging-ReG/public/browse_detail_2.php on line
385
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
471
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
472
Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 751
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 754
Warning: Undefined variable $pathway_id in /data/html/Aging-ReG/public/browse_detail_2.php on line 793