External factors
| Category: |
Chemical compounds |
| Experiment: |
SA-β-gal activity assay//BrdU Assay |
| Description: |
Not all polyploid cells underwent apoptosis in the presence of R1530. A substantial fraction remained viable but stopped replication and acquired a senescence phenotype.The representative cell in the time-lapse sequence ceased to proliferate after one cycle of abortive mitosis/endo-reduplication but continued to grow and nearly tripled its initial size. These morphological changes correlated very well with the decrease in the BrdU labeling index and the kinetics of staining for senescence-associated β-galactosidase activity (SA-β-Gal), the most widely recognized senescence marker11. |
Warning: Undefined variable $target_genes in
/data/html/Aging-ReG/public/browse_detail_2.php on line
385
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
471
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
472
Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 751
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 754
Warning: Undefined variable $pathway_id in /data/html/Aging-ReG/public/browse_detail_2.php on line 793