External factors
| Category: |
Chemical compounds |
| Phenotype: |
Hepatocellular carcinoma |
| Experiment: |
SA-β-gal activity assay//Flow cytometry//Cell morphological analysis |
| Description: |
We acquired only SMMC?772 cells treated with rapamycin and 5?Fu in combination exhibited the distinctive morphology of senescent cells and were positive for senescence?associated β?galactosidase(SA?β?Gal), a hallmark of senescent cells24 .5?Fu treatment on SMMC?772 cells caused a significant loss of the cell cycle S/G2/M phase, addition of rapamycin induced a G arrest in SMMC?772 cells. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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