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Aging Overview

External factors

External factors: H2O2
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Beta Thalassemia
Experimental category: L
Tissue type: Blood
Cell name: Erythrocyte
PMID: 23383265
Experiment: Osmotic tolerance test
Description: Percent hemolysis of H2O2-treated erythrocytes was only 2.0±0.3% after exposure to hypotonic solution.According to Freikman et al.[27], a reduction in hemolysis of erythrocytes after hypotonic solution challenge is considered as an indicator of oxidative stress-induced erythrocyte aging.



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Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.




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