External factors
| External factors: |
Salvia haenkei |
| Category: |
Chemical compounds |
| Experiment: |
SA-β-gal activity assay//Cell viability assay |
| Description: |
While untreated cells stopped growing at passage 30,cells treated with SH continued to proliferate. Moreover,senescence in treated cells was significantly decreased when compared to control as assessed by the SA-β-Gal staining.The reduction in the percentage of SA-β-Gal staining in these cells was comparable to the one observed in Pten null MEFs showing a correspondence between these two models. Importantly, treatment of cells with SH for a period of three months was not associated to increased cell death, as demonstrated by the cell viability assay. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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