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Aging Overview

External factors

External factors: VAS-2870
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: Endothelial cell
PMID: 26672612
Experiment: SA-β-gal activity assay//Western blot
Description: The fact that NAC, NADPH oxidase inhibitors (apocynin and VAS-2870), and indomethacin significantly reduced SA-β-gal activity, and also the increased expression of the senescence markers (p53, p21, and p16).



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Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.




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