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Aging Overview

External factors

External factors: GlyH-101
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Beta Thalassemia
Experimental category: L
Tissue type: Blood
Cell name: Erythrocyte
PMID: 23383265
Experiment: Osmotic tolerance test
Description: However,percent hemolysis of GlyH-101-treated erythrocytes was 5.9±1.3% (p,0.05) after exposure to hypotonic solution.According to Freikman et al. [27], a reduction in hemolysis of erythrocytes after hypotonic solution challenge is considered as an indicator of oxidative stress-induced erythrocyte aging.



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Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.




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