External factors
| External factors: |
Estrogen |
| Category: |
Chemical compounds |
| Tissue type: |
Bone marrow,Bone |
| Cell name: |
MSC,Chondrocyte |
| Experiment: |
Telomere length assay//Southern blot |
| Description: |
Telomere length declined over the entire observation period for all experimental groups to values ranging from 6.4 to 9.8 kbp,with increasing concentrations of E2 treatment, mean telomere shortening decreased(MSCs).Telomere length declined for all experimental groups to values ranging from 8.2 to 10.2 kbp. Telomere shortening correlated with cpd (P < 0.001). With increasing concentrations of E2 treatment, mean telomere shortening decreased(Human chondrocytes). |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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