External factors
| External factors: |
Paclitaxel |
| Category: |
Chemical compounds |
| Phenotype: |
Gastric cancer |
| Experiment: |
SA-β-gal activity assay//Flow cytometry |
| Description: |
SA-β-galactosidase activity staining showed a clear increase in cellular senescence in these cells after PTX treatment compared with control MKN45 cells. PTX causes a prometaphase arrest cell cycle that, if sustained, generates DNA damage and senescence. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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