External factors
| External factors: |
Palmitic acid |
| Category: |
Chemical compounds |
| Experiment: |
qPCR//SA-β-gal activity assay//Western blot |
| Description: |
PA treatment led to a reduction of SMARCD1 expression in HepG2 cell, and induced cellular senescence in HepG2 cells, demonstrated by an increased number of cells with high levels of SA-β-Gal activity, p16/p21 expression, p-p38 expression, and γH2AX expression in the PA-treated HepG2 cells. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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