External factors
| External factors: |
Caffeine |
| Category: |
Chemical compounds |
| Experiment: |
SA-β-gal activity assay//SAHF//Western blot |
| Description: |
We found that caffeine indeed inhibited AAPH-induced increase in the SA β-Gal activity in A375 and NIH3T3 cells. Further, caffeine suppressed AAPH-induced SAHF formation in A375 cells, increases in p53 phosphorylation and p21 protein levels both in A375 and in NIH3T3 cells. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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