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Aging Overview

External factors

External factors: C-phycocyanin
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: Kidney,Spleen,Ovary
Cell name: --
PMID: 27008700
Experiment: Cell morphological analysis
Description: Surprisingly, the organ coefficients of ovary, spleen, and kidney from control and D-gal+PC groups were higher than those of the D-gal group .These data indicate that D-gal may impair the ovary, spleen, and kidney, and that this damage can be reversed partially by PC.Conversely, after PC administration most D-gal-induced oocytes showed normal morphology, similar to the control group . For both the in vivo and in vitro maturation models, we found that the aneuploidy rate of sister chromatids was higher in the D-gal group compared to control (P < 0.001). After PC administration, decreased percentages of aneuploidy oocytes were observed both in vivo and in vitro (P < 0.001).



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Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.




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