External factors
| External factors: |
Atorvastatin |
| Category: |
Chemical compounds |
| Cell name: |
Endothelial cell |
| Experiment: |
Flow cytometry//PCR//SA-β-gal activity assay//Telomerase activity assay |
| Description: |
Increase in ROS formation was significantly reduced by atorvastatin. Incubation with atorvastatin also inhibited the loss of intact mitochondrial DNA and abrogated the reduction of nuclear and overall TERT activity and protein. Furthermore, incubation with atorvastatin delayed the onset of senescence of endothelial cells . |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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