External factors
| External factors: |
Doxorubicin |
| Category: |
Chemical compounds |
| Phenotype: |
Gastric cancer |
| Experiment: |
SA-β-gal activity assay//Flow cytometry//SAHF//Cell morphological analysis |
| Description: |
After treatment, most cells became flattened and had comparatively enlarged morphology. Positive level of senescence-associated SA-β-gal staining was increased in AGS cells; SAHF formation increased in treated MKN28 cells. Flow cytometry analysis demonstrated that proportions of cells in G0/G1 phase ncreased in treated cells. In MKN28 cells, we also noticed a significant increase in proportions of cells in G2/M . |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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