External factors
| External factors: |
Cilostazol |
| Category: |
Chemical compounds |
| Experiment: |
SA-β-gal activity assay |
| Description: |
Treatment with cilostazol inhibited the senescent phenotype induced by sirolimus or everolimus at 10 days. Under treatment with sirolimus or everolimus (2.5 nmol/l), 49.2% or 53.0% of cells were SA-βgal positive, versus only 13.6% or 14.6% of cilostazol (100 μmol/l)-treated cells under the same conditions. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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