External factors
| External factors: |
4 hydroxytamoxifen |
| Category: |
Chemical compounds |
| Experiment: |
SA-β-gal activity assay |
| Description: |
The MCF7 cells adhered to the etched coverslips and essentially grew as colonies. After 6 days, the cells on the coverslips were processed for β-galactosidase staining as described [109]. Both doxorubicin (10-100 nM) and 4HT (50-1000 nM) induced senescence in MCF-7 cells in a dose-dependent fashion. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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