External factors
| External factors: |
UVB irradiation |
| Experiment: |
MTT assay//SA-β-gal activity assay |
| Description: |
Incremental doses of UVB cause cellular viability decline dose-dependently and at 296 to 696 mJ/cm2doses, the inhibitory effects were significant (P< 0.001);The proportion of positive β-galactosidase cells among UVB-irradiated cells was significantly (P < 0.01) greater than among non-irradiated ones. |
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Regulatory relationship
| R-EF-Target gene:
|
Upregulation |
| Official symbol(s): |
FOXO3A |
| Target gene experiment: |
qPCR |
| Target gene description: |
UVB irradiation significantly upregulated the FOXO3A expression compared to the control cells . |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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