External factors
| External factors: |
Fluidic substrate |
| Experiment: |
Cell viability assay//Cell cycle analysis |
| Description: |
The viability of the cancer cells on non-crosslinked P(CL-co-DLLA) substrates was significantly decreased to 57% and 32% for 48 h and 72 h respectively.Cells on crosslinked P(CL-co-DLLA) substrate showed a reduced G0/G1 phase (13.87%) and increased S phase (75.55%). However, cells on non-crosslinked P(CL-co-DLLA) substrate showed an accumulation of G0/G1 phase (66.3%) and reduction of S phase (13.92%). |
Warning: Undefined variable $target_genes in
/data/html/Aging-ReG/public/browse_detail_2.php on line
385
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
383
Regulatory relationship
| R-EF-Target gene:
|
Upregulation//Upregulation |
| Official symbol(s): |
IGFBP5//P53 |
| Target gene experiment: |
Immunofluorescence//Confocal microscopy//RT-PCR |
| Target gene description: |
At 72 h, cells on the non-crosslinked P(CL-co-DLLA) substrate showed a significant induction of IGFBP5 mRNA .At day 3, p53 bands were significant only for cells grown on the non-crosslinked P(CL-co-DLLA) substrate. |
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
471
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
472
Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 751
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 754
Warning: Undefined variable $pathway_id in /data/html/Aging-ReG/public/browse_detail_2.php on line 793