External factors
| External factors: |
Radiation |
| Experiment: |
SA-β-gal activity assay |
| Description: |
HUVECs treated with low doses of ionizing radiation showed a significant increase in SA-β-gal+ cells in a dose-dependent manner (p?
|
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Regulatory relationship
| R-EF-Target gene:
|
Downregulation//Upregulation |
| Official symbol(s): |
KU86//P16 |
| Target gene experiment: |
Western blot |
| Target gene description: |
We also found that the increased ionization caused a significant reduction in Ku86 expression and a significant increase in p16Ink4a expression in a dose-dependent manner. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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