External factors
| External factors: |
Lipid lowering therapy |
| Phenotype: |
Coronary artery disease |
| Experimental category: |
HL |
| Description: |
The aggressive LLT group showed reduced LDL cholesterol levels in CAD patients after 12 months of therapy. |
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Regulatory relationship
| Target gene:
|
MIR-23A//TRF2 |
| R-EF-Target gene:
|
Downregulation//Upregulation |
| Official symbol(s): |
MIR-23A//TERF2 |
| Target gene experiment: |
qRT-RCR//Flow cytometry |
| Target gene description: |
Aggressive LLT markedly decreased levels of miR-23a (2.78±1.29 vs. 2.09 ±1.17, P < 0.01) and increased levels of TRF2 (2.98 ± 1.44 vs.3.52 ± 1.34, P < 0.01). |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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