External factors
| Category: |
Chemical compounds |
| Experimental category: |
HL |
| Experiment: |
SA-β-gal activity assay//Cell morphological analysis//SAHF |
| Description: |
A significantly enlarged cell size, increased SA-β-gal activity, and increased SAHF in cells treated with 50 nM DOX for 4 days were noted. |
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Regulatory relationship
| R-EF-Target gene:
|
Upregulation |
| Official symbol(s): |
MIR-375 |
| Target gene experiment: |
qRT-PCR |
| Target gene description: |
By comparing miRNA expression profiles between treated and untreated K562 cells, 10 upregulated miRNAs were found in DOX-treated K562 cells .The expression of miR-375 remained to be the highest among the 4 miRNAs . |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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