External factors
| Category: |
Chemical compounds |
| Experiment: |
Cell morphological analysis//SA-β-gal activity assay |
| Description: |
We found that PMA caused a large flat morphology with nucleoli enlargement and beta-Gal positivity . |
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Regulatory relationship
| Target gene:
|
P21//CYCLIN D1 |
| R-EF-Target gene:
|
Activation//Activation |
| Official symbol(s): |
P21//CYCLIN D1 |
| Target gene experiment: |
Western blot |
| Target gene description: |
PMA rapidly activated ERK1/2 followed by p21 and cyclin D1 induction. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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