External factors
| External factors: |
LY294002 |
| Category: |
Chemical compounds |
| Experiment: |
SA-β-gal activity assay//Cell morphological analysis |
| Description: |
LY294002 decreased intensity of SA-β-Gal staining but did not abrogate it completely . Cells remained flat, with a typical nuclear appearance.LY294002 suppressed senescence. |
Warning: Undefined variable $target_genes in
/data/html/Aging-ReG/public/browse_detail_2.php on line
385
Regulatory relationship
| Regulatory pathway:
|
mTOR-S6 |
| R-EF-Pathway:
|
Downregulation |
| Official symbol(s): |
Warning: Undefined variable $name_all in /data/html/Aging-ReG/public/browse_detail_2.php on line 525
MTOR
|
| Pathway experiment: |
Western blot |
| Pathway description: |
Like rapamycin, LY294002 inhibited S6 phosphorylation at day 1 . |
Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.