External factors
| Category: |
Chemical compounds |
| Experiment: |
Cell morphological analysis |
| Description: |
U0126 suppressed senescence. |
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Regulatory relationship
| Regulatory pathway:
|
mTOR-S6 |
| R-EF-Pathway:
|
Downregulation |
| Official symbol(s): |
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MTOR
|
| Pathway experiment: |
Western blot |
| Pathway description: |
As expected, U0126 inhibited ERK phosphorylation (day 1).Like rapamycin, U0126 inhibited S6 phosphorylation at day 1 . |
Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.