External factors
| External factors: |
Phenolic diterpenes carnosol |
| Category: |
Chemical compounds |
| Tissue type: |
Mammary Gland |
| Experiment: |
MTT assay//SA-β-gal activity assay |
| Description: |
The pre-incubation with CA conferred a significant protection against H2O2-induced cell growth inhibition and the appearance of SA-β-gal positive cells. |
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Regulatory relationship
| R-EF-Pathway:
|
Upregulation |
| Official symbol(s): |
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NFE2L2
|
| Pathway experiment: |
Western blot |
| Pathway description: |
CS increased the levels of Nrf2 in the nuclear fractionTreatment of ASF-2 cells with CS significantly increased the transcriptional activity of Nrf2. |
Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.