External factors
| Experiment: |
Western blot//SA-β-gal activity assay |
| Description: |
Infection of VSVG-HIV also caused a 1.8-fold increase in p16INK4Alevels .Transfection of HFAs with HIVBal plasmid induced SA‐β-Gal+ cells from 8% in pcDNA3 control plasmid to 20% in HIV‐transfected cells. |
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Regulatory relationship
| Regulatory pathway:
|
β-catenin |
| R-EF-Pathway:
|
Downregulation |
| Official symbol(s): |
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CTNNBIP1
|
| Pathway experiment: |
Western blot//SA-β-gal activity assay |
| Pathway description: |
HIV also inhibited β-catenin signaling in HFA, as demonstrated by inhibition of Activate β-catenin expression post-VSVG-HIV infection to 30% at 48 h and 22% at 72 h of the VSVG control. |
Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.