External factors
| Category: |
Chemical compounds |
| Phenotype: |
Cardiovascular disease |
| Cell name: |
Endothelial cell |
| Experiment: |
SA-β-gal activity assay |
| Description: |
As the concentrations of OX-LDL increased, the number of β-galactosidase-positive cells increased significantly, reaching a maximal value at 100 mg/mL OX-LDL. |
Warning: Undefined variable $target_genes in
/data/html/Aging-ReG/public/browse_detail_2.php on line
385
Regulatory relationship
| R-EF-Target gene:
|
Downregulation |
| Official symbol(s): |
SIRT1 |
| Target gene experiment: |
Western blot |
| Target gene description: |
At this concentration of OX-LDL, the SIRT1 protein expression was significantly decreased as compared to control cells. |
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
471
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
472
Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 751
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 754
Warning: Undefined variable $pathway_id in /data/html/Aging-ReG/public/browse_detail_2.php on line 793