External factors
| External factors: |
Trans-Cinnamaldehyde |
| Category: |
Chemical compounds |
| Experimental category: |
HL |
| Experiment: |
Immunostaining//SA-β-gal activity assay//ELISA |
| Description: |
We found that the number of Ki-67 positive cells was dramatically decreased after H2O2 induction,however, the number of Ki-67 positive cells was greatly enhanced by subsequent TC treatment;The percentage of SA-β-gal positive cells was decreased dramatically when H2O2-induced cells were treated with TC, confirming its anti-senescent effects ;The TC-treated ADSCs post H2O2 treatment showed increased telomerase activity when compared to the H2O2 group. |
Warning: Undefined variable $target_genes in
/data/html/Aging-ReG/public/browse_detail_2.php on line
385
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
383
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
383
Regulatory relationship
| Target gene:
|
SIRT1//P53//P21 |
| R-EF-Target gene:
|
Upregulation//Downregulation//Downregulation |
| Official symbol(s): |
SIRT1//P53//P21 |
| Target gene experiment: |
Semi-qPCR//qPCR |
| Target gene description: |
Upregulation of SIRT1 in TC-treated ADSCs post H2O2 treatment is a vital indicator of antisenescence capacity of TC ;When rescued by TC treatment, the expression of p21 and p53 seemed to reduce. |
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
471
Warning: Trying to access array offset on null in
/data/html/Aging-ReG/public/browse_detail_2.php on line
472
Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 751
Warning: Trying to access array offset on null in /data/html/Aging-ReG/public/browse_detail_2.php on line 754
Warning: Undefined variable $pathway_id in /data/html/Aging-ReG/public/browse_detail_2.php on line 793